Aripiprazole as a potential pharmacotherapy for stimulant dependence: Human laboratory studies with d-amphetamine.

Amphetamine and cocaine dependence present significant public health concerns, yet no broadly effective pharmacotherapy for stimulant dependence has been developed. Two human laboratory studies are reviewed that tested the ability of aripiprazole, a novel antipsychotic with partial agonist activity at D2 dopamine receptors, to alter the behavioral effects of stimulants using d-amphetamine as a model agent. In each of these experiments, volunteers learned to discriminate 15 mg d-amphetamine (i.e., ≥80% drug-appropriate responding over 4 consecutive sessions). The effects of a range of doses of d-amphetamine (0, 2.5, 5, 10, and 15 mg) were then tested alone and following pretreatment with aripiprazole (20 mg in Experiment 1; 10 mg in Experiment 2). In Experiment 1, aripiprazole (20 mg) attenuated the discriminative stimulus and many of the subject-rated effects of amphetamine. Aripiprazole alone produced performance decrements. To determine whether a lower dose of aripiprazole would also attenuate the behavioral effects of d-amphetamine without impairing performance, Experiment 2 was conducted. Aripiprazole (10 mg) failed to alter the discriminative-stimulus effects but attenuated some of the subject-rated effects of d-amphetamine. This dose of aripiprazole did not impair performance. The results of these experiments indicate that aripiprazole may have clinical utility in treating stimulant dependence. Future human laboratory research should better model the clinical use of aripiprazole by examining the effects of chronic aripiprazole combined with either methamphetamine or cocaine in dependent individuals. A large-scale clinical trial is also needed to evaluate the efficacy of aripiprazole for the treatment of stimulant dependence. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

500kW／380V国产大功率变频器在钻机上的应用

针对国外变频器价格昂贵、调试周期和维修周期长等特点，我公司自主研发了可替代进口机的高性能钻机国产专用变频器。该变频器能够从零开始调速。当钻井卡钻时，能及时断开电动机，在低速提升时，能最大限度地发挥电动机的动力特性，提供220％的转矩输出。变频器具有易安装、调试、维护，性能稳定。应用中据实测数据显示，采用变频改造后，打1口井可节省柴油15t。     

丙烯腈－苯乙烯共聚物水解磺化产物对泥浆的稳定作用

在实验室条件下对用丙烯腈－苯乙烯共聚物在硫酸存在下的水解磺化产物（ＨＳＡＳ）处理的泥浆性能进行了评定。ＨＳＡＳ处理的泥浆有较小的滤失性，较好的耐盐和抗高温性。     

Artificial neural networks for coordination and control: The portability of experiential representations

It is time to locate connectionist representation theory in the new wave of robotics research. The utility of representations developed in artificial neural networks (ANNs) during learning has been demonstrated in cognitive science research since the 1980s. The research reported here puts learned representations to work in a decentered control task, the disembodied arm problem, in which a mobile robot operates an arm fixed to a table to pick up objects. There is no physical linkage between the arm and the robot and so the robot's point of view must be decentered. This is done by developing a modular Artificial Neural Net system in three stages: (i) a classifier net is trained with laser scan data to output transformationally invariant position classes; (ii) an arm net is trained for picking up objects; (iii) an inter net is trained to communicate and coordinate the sensing and acting. The completed system is shown to create new nonsymbolic transformationally invariant representations in order to perform the effective generalization of decentered viewpoints.     

插补法CAI研究

数字程序控制计算机辅助教学是将计算机技术用于数字程序控制的教学过程，它帮助学生学习并模拟教学实验．本文介绍了数字程序控制中直线插补和圆孤插补的ＣＡＩ实现方法．     

鄱阳湖控制浅说

该控制工程主要效益是改变鄱阳湖“夏水冬陆”的现状，成为祖国名符其实的第一大淡水湖，水面与避署胜地庐山和历史名城南昌、景德镇等相连，改善沿湖环境，发展航运，增加水产，开发利用丰富的水资源和旅游资源使之与杭州西湖、瑞士日内瓦湖等并列为世界名湖。     

现场总线技术在城市污水处理与气象中的应用

文章主要讨论了LonWorks现场总线技术在城市污水处理厂和气象指数预报中的应用。采用IPC和PLC控制结构对现场的各种设备实现控制和数据的采集，通过现场总线网络传输数据到中心控制室或远程终端，实现污水处理的自动控制和气象信息的实时采集和处理。     

飞机液压系统污染及控制

本文全面分析了收音机液压系统污染的危害和主要原因，并在此基础上有针对性地提出了预防措施。     

数据采集与监控软件Genie

Genie是具有国际先进水平的数据采集与监控软件，它提供了一个面向对象的图形化用户界面，因此简化了数据采集过程、控制应用程序开发和操作员界面。本文介绍了Genie的特点、功能、基本用途以及VISUALBA－SIC在设计这类监控软件中的作用。     

基于PⅢ工控机VI测控系统远程控制研究

虚拟仪器（VI）将计算机采集测试分析引入到电子测量领域，用数字化和软件技术极大地提高了测量的灵活性。而VI远程测控系统是网络技术、通信技术一计算机虚拟技术结合的产物。远程控制技术能够使操作突破地域的限制，已在网络环境下PⅢ工控机上实现。